Trends and Patterns of Pancreatic Cancer Prevalence at Benghazi Medical Center: A Retrospective Analysis (2018–2024)

Nagwa Mohamed; Tareq Lehmidi; Lobna Elfergani; Aya Albadry; Ghada Alramly; Hajer Aishhebi; Nada Alqetrani; Abeer Amer

doi:10.54361/ajmas.258337

Authors

Nagwa Mohamed Department of Physiology, Faculty of Medicine, University of Benghazi, Benghazi, Libya https://orcid.org/0009-0002-9148-6087
Tareq Lehmidi Department of Pathology, Faculty of Medicine, University of Benghazi, Benghazi, Libya https://orcid.org/0009-0006-0787-5581
Lobna Elfergani Department of Histology, Faculty of Medicine, University of Benghazi, Benghazi, Libya https://orcid.org/0000-0003-3713-9885
Aya Albadry Department of Cytotechnology, Faculty of Biomedical Sciences, University of Benghazi, Benghazi, Libya https://orcid.org/0009-0009-9521-8208
Ghada Alramly Department of Cytotechnology, Faculty of Biomedical Sciences, University of Benghazi, Benghazi, Libya https://orcid.org/0000-0003-4289-1481
Hajer Aishhebi Department of Cytotechnology, Faculty of Biomedical Sciences, University of Benghazi, Benghazi, Libya https://orcid.org/0009-0000-4736-1995
Nada Alqetrani Department of Cytotechnology, Faculty of Biomedical Sciences, University of Benghazi, Benghazi, Libya https://orcid.org/0000-0003-0137-8374
Abeer Amer Department of Histology, Faculty of Medicine, University of Benghazi, Benghazi, Libya. Department of Histology, Medicine and Surgery Program, Hespereds University, Benghazi, Libya https://orcid.org/0000-0002-7311-0177

DOI:

https://doi.org/10.54361/ajmas.258337

Keywords:

Pancreatic Cancer, Demographic Characteristics, Histological Subtypes, Late-Stage Diagnosis, Epidemiology, Benghazi Medical Center.

Abstract

Pancreatic cancer is a highly lethal malignancy with a poor prognosis worldwide. Despite its clinical importance, there is limited regional data available regarding its demographic and histopathological patterns in Libya. This study aimed to analyze the demographic characteristics, clinical presentation, and histological subtypes of pancreatic cancer in patients admitted to Benghazi Medical Center between 2018 to 2024. A cross-sectional analysis was conducted on 114 cases of histologically confirmed pancreatic cancer. Data were collected from hospital archives after obtaining ethical approvals. The variables assessed included age, gender, geographic location, disease stage at diagnosis, and histopathological subtypes. Descriptive statistical analysis was conducted utilizing Microsoft Excel 2016. The incidence of pancreatic cancer peaked in the 55–64 age group, with a notable male predominance. Most cases originated from Benghazi, followed by Al-Baida and Al-Maraj. The majority of patients (66.67%) presented with advanced-stage (Stage 4) disease at the time of diagnosis. The most common subtype in terms of histology was adenocarcinoma (65%), which was followed by intraductal papillary mucinous neoplasm (23%). These findings highlight the predominance of late-stage diagnosis and underscore significant demographic and histological trends in pancreatic cancer within the studied population. Further research is warranted to explore factors contributing to gender disparities and regional variations in incidence.